![]() They act via serotonin 2A receptor agonism. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides (LSD is considered both a tryptamine and lysergamide). In particular, LSD has long been considered the paradigmatic psychedelic compound to which all other psychedelics are often or usually compared. The "classical" psychedelics, the psychedelics with the largest scientific and cultural influence, are mescaline, LSD, psilocybin, and DMT. Psychedelic states are often compared to meditative, psychodynamic or transcendental types of alterations of the mind. ![]() True psychedelics cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. Sometimes, they are called classic hallucinogens, serotonergic hallucinogens, or serotonergic psychedelics, and the term psychedelic is sometimes used more broadly to include various types of hallucinogens or those which are atypical or adjacent to psychedelia such as MDMA or cannabis this article uses the narrower definition of psychedelics. ![]() Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or psychedelic "trips") and/or an apparent expansion of consciousness. Normally biosynthesized from peyote and some other cacti, mescaline was the first psychedelic compound to be extracted and isolated.
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